There is variability in the reported effects of compounds on osteoblasts arising from differences in experimental design and choice of cell type/origin.This makes it difficult to discern a compound’s action outside its original study and compare efficacy between compounds.Here, we investigated five compounds frequently reported as anabolic fo
Understanding mechanisms associated to dendritic cell (DC) functions has allowed developing new antitumor therapeutic vaccination strategies.However, these vaccines have demonstrated limited clinical results.Although the low immunogenicity 5-HTP of tumor antigens used and the presence of tumor-associated suppressive factors may in part account for
In addition to its role in the endogenous synthesis of cysteine, cystathionine gamma-lyase (CGL) is a major physiological source of the vasorelaxant hydrogen sulfide.Cgl null mice are potentially useful for studying the influence of this compound upon vascular tone and endothelial function.Here, we confirm a previous report that female Cgl null mic